RASGRP2 Antikörper (AA 7-34)

Produktnummer ABIN7876487

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch RASGRP2 in WB, IF und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für RASGRP2 Antikörper (AA 7-34) (ABIN7876487)

Target: RASGRP2 (RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RASGRP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-RASGRP2 Antikörper

Bindungsspezifität: AA 7-34

Verwendungszweck: CalDAG-GEFI Antibody / RASGRP2

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 7-34 from the human protein was used as the immunogen for the CalDAG-GEFI antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the CalDAG-GEFI antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the CalDAG-GEFI antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu RASGRP2

Target: RASGRP2 (RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2))

Andere Bezeichnung: CalDAG-GEFI

Hintergrund: The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Three alternatively spliced transcript variants encoding the same protein have been found for this gene.

UniProt: Q7LDG7

Pathways: T-Zell Rezeptor Signalweg