RASL12 Antikörper (AA 7-261)

Produktnummer ABIN7876474

Der Kaninchen Polyklonal anti-RASL12 Antikörper (ABIN7876474) detektiert spezifisch RASL12 in ELISA, WB, FACS, ICC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für RASL12 Antikörper (AA 7-261) (ABIN7876474)

Target: RASL12 (RAS-Like, Family 12 (RASL12))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RASL12 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)

Produktdetails anti-RASL12 Antikörper

Bindungsspezifität: AA 7-261

Verwendungszweck: RASL12 Antibody / Ras-like protein family member 12

Aufreinigung: Immunogen affinity purified

Immunogen: E.coli-derived human RASL12 recombinant protein (Position: K7-K261) was used as the immunogen for the RASL12 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the RASL12 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the RASL12 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu RASL12

Target: RASL12 (RAS-Like, Family 12 (RASL12))

Andere Bezeichnung: RASL12

Hintergrund: RASL12 antibody detects Ras-like protein family member 12, encoded by the RASL12 gene. Ras-like protein family member 12 is a small GTP binding protein that belongs to the Ras superfamily, which regulates signal transduction, cell growth, and cytoskeletal organization. RASL12 antibody provides researchers with a specific reagent for studying small GTPases and their influence on cellular signaling and differentiation.

Ras-like protein family member 12 is less well characterized than classical Ras proteins, but research using RASL12 antibody has shown that it retains the conserved GTP binding and hydrolysis domains characteristic of the Ras family. Through these domains, it likely regulates intracellular signaling cascades linked to growth, adhesion, and movement. Expression studies have shown that RASL12 is present in multiple tissues, suggesting broad cellular roles.

Studies with RASL12 antibody have revealed that Ras-like protein family member 12 may regulate cell cycle progression and survival pathways. Its sequence homology to other Ras proteins suggests involvement in MAPK and PI3K signaling networks, although specific effectors remain under investigation. Understanding the role of RASL12 may uncover new mechanisms of Ras family signaling and its impact on development and disease.

Dysregulation of RASL12 has been linked to tumor biology. Research using RASL12 antibody has demonstrated altered expression patterns in certain cancers, where imbalance may contribute to abnormal proliferation and survival. These findings support further investigation into its potential as a cancer biomarker and therapeutic target.

RASL12 antibody is commonly applied in western blotting, immunohistochemistry, and immunofluorescence. Western blotting detects endogenous expression in tissues and cell lines, immunohistochemistry reveals tissue-specific localization, and immunofluorescence highlights subcellular distribution. These approaches make RASL12 antibody valuable for research into Ras signaling networks.

By providing validated RASL12 antibody reagents, NSJ Bioreagents supports studies into Ras superfamily proteins, signal transduction, and cancer. Detection of Ras-like protein family member 12 offers researchers insight into how small GTPases integrate cellular signaling.

UniProt: Q9NYN1