Adrenomedullin Antikörper (AA 69-96)

Produktnummer ABIN7876453

Der Kaninchen Polyklonal anti-Adrenomedullin Antikörper (ABIN7876453) detektiert spezifisch Adrenomedullin in WB und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Adrenomedullin Antikörper (AA 69-96) (ABIN7876453)

Target: Adrenomedullin (ADM)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Adrenomedullin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Produktdetails anti-Adrenomedullin Antikörper

Bindungsspezifität: AA 69-96

Verwendungszweck: Adrenomedullin antibody / ADM

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 69-96 from the human protein was used as the immunogen for the Adrenomedullin antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the Adrenomedullin antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Adrenomedullin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu Adrenomedullin

Target: Adrenomedullin (ADM)

Andere Bezeichnung: Adrenomedullin

Substanzklasse: Hormone

Hintergrund: ADM, a hypotensive peptide found in human pheochromocytoma, consists of 52 amino acids, has 1 intramolecular disulfide bond, and shows a slight homology with the calcitonin gene-related peptide. It may function as a hormone in circulation control because it is found in blood in a considerable concentration. The precursor, called preproadrenomedullin, is 185 amino acids long. By RNA-blot analysis, human adrenomedullin mRNA was found to be highly expressed in several tissues. Genomic ADM DNA consists of 4 exons and 3 introns, with the 5-prime flanking region containing TATA, CAAT, and GC boxes.

UniProt: P35318

Pathways: Hormone Transport, Hormone Activity, C21-Steroid Hormone Metabolic Process, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Tube Formation