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Adrenomedullin Antikörper (N-Term)

ADM Reaktivität: Human, Ratte, Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6259801
  • Target Alle Adrenomedullin (ADM) Antikörper anzeigen
    Adrenomedullin (ADM)
    Bindungsspezifität
    • 15
    • 15
    • 9
    • 8
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 57
    • 49
    • 14
    • 7
    • 7
    • 1
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 106
    • 10
    • 2
    • 1
    Kaninchen
    Klonalität
    • 109
    • 10
    Polyklonal
    Konjugat
    • 53
    • 20
    • 12
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser Adrenomedullin Antikörper ist unkonjugiert
    Applikation
    • 55
    • 37
    • 32
    • 26
    • 26
    • 12
    • 9
    • 9
    • 8
    • 8
    • 7
    • 6
    • 4
    • 3
    • 3
    Western Blotting (WB), ELISA
    Spezifität
    ADM Antibody detects endogenous levels of total ADM.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human ADM, corresponding to a region within N-terminal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product ADM Primärantikörper
  • Applikationshinweise
    WB 1:500-2000, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    Adrenomedullin (ADM)
    Andere Bezeichnung
    ADM (ADM Produkte)
    Synonyme
    ADM antikoerper, Ap antikoerper, H39316 antikoerper, RATAP antikoerper, AM antikoerper, adrenomedullin antikoerper, ADM antikoerper, adm antikoerper, Adm antikoerper
    Substanzklasse
    Hormone
    Hintergrund

    Description: AM and PAMP are potent hypotensive and vasodilatator agents. Numerous actions have been reported most related to the physiologic control of fluid and electrolyte homeostasis. In the kidney, am is diuretic and natriuretic, and both am and pamp inhibit aldosterone secretion by direct adrenal actions. In pituitary gland, both peptides at physiologically relevant doses inhibit basal ACTH secretion. Both peptides appear to act in brain and pituitary gland to facilitate the loss of plasma volume, actions which complement their hypotensive effects in blood vessels.

    Gene: ADM

    Molekulargewicht
    20 kDa
    Gen-ID
    133
    UniProt
    P35318
    Pathways
    Hormone Transport, Hormone Activity, C21-Steroid Hormone Metabolic Process, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Tube Formation
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