Adrenomedullin Antikörper (Internal Region)

Produktnummer ABIN7219580

Der Kaninchen Polyklonal anti-Adrenomedullin Antikörper (ABIN7219580) detektiert spezifisch Adrenomedullin in IHC, ELISA und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte und Maus.

Kurzübersicht für Adrenomedullin Antikörper (Internal Region) (ABIN7219580)

Target: Adrenomedullin (ADM)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Adrenomedullin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-Adrenomedullin Antikörper

Bindungsspezifität: Internal Region

Verwendungszweck: Rabbit Anti-ADM Polyclonal Antibody

Spezifität: ADM Polyclonal Antibody detects endogenous levels of ADM protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human ADM

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Adrenomedullin

Target: Adrenomedullin (ADM)

Andere Bezeichnung: ADM

Substanzklasse: Hormone

Hintergrund: ADM, AM, ADMThe adrenomedullin encoded by ADM is a preprohormone which is cleaved to form two biologically active peptides, adrenomedullin and proadrenomedullin N-terminal 20 peptide. Adrenomedullin is a 52 aa peptide with several functions, including vasodilation, regulation of hormone secretion, promotion of angiogenesis, and antimicrobial activity. The antimicrobial activity is antibacterial, as the peptide has been shown to kill E.coli and S. aureus at low concentration.

Gen-ID: 133

UniProt: P35318

Pathways: Hormone Transport, Hormone Activity, C21-Steroid Hormone Metabolic Process, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Tube Formation