LTB Antikörper (AA 68-306)

Produktnummer ABIN7876397

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch LTB in WB, ELISA und FACS. Es zeigt Reaktivität gegenüber Proben von Maus und Ratte.

Kurzübersicht für LTB Antikörper (AA 68-306) (ABIN7876397)

Target: LTB (Lymphotoxin beta (TNF Superfamily, Member 3) (LTB))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LTB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-LTB Antikörper

Bindungsspezifität: AA 68-306

Verwendungszweck: Lymphotoxin beta Antibody / Ltb

Aufreinigung: Antigen affinity purified

Immunogen: An E.coli-derived mouse recombinant protein (amino acids R68-G306) was used as the immunogen for the Lymphotoxin beta antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Lymphotoxin beta antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Lymphotoxin beta antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu LTB

Target: LTB (Lymphotoxin beta (TNF Superfamily, Member 3) (LTB))

Andere Bezeichnung: Lymphotoxin beta

Hintergrund: Lymphotoxin-beta (LT-beta) also known as tumor necrosis factor C (TNF-C) is a protein that in humans is encoded by the LTB gene. Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 Molecule alpha/2 Molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms.

UniProt: P41155

Pathways: NF-kappaB Signalweg