HSPH1 Antikörper (AA 653-858)

Produktnummer ABIN7876321

Der Maus Monoklonal anti-HSPH1 Antikörper (Klon 3D10) (ABIN7876321) detektiert spezifisch HSPH1 in WB, IF, IHC (p) und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für HSPH1 Antikörper (AA 653-858) (ABIN7876321)

Target: HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HSPH1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Klon: 3D10

Produktdetails anti-HSPH1 Antikörper

Bindungsspezifität: AA 653-858

Verwendungszweck: Hsp105 Antibody

Aufreinigung: Affinity purified

Immunogen: A human recombinant protein (amino acids Y653-D858) was used as the immunogen for the Hsp105 antibody.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Hsp105 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Hsp105 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu HSPH1

Target: HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))

Andere Bezeichnung: Hsp105

Hintergrund: HSP105 (HEAT-SHOCK 105/110-KD PROTEIN 1), also called HSPH1 or HSP110, is a protein that in humans is encoded by the HSPH1 gene. Immunohistochemical analysis localizes HSP105 mainly in the cytoplasm. Database analysis indicates that both HSP105 isoforms are highly conserved during evolution. By analysis of radiation hybrids and human/rodent hybrid cell lines, the HSPH1 gene is mapped to chromosome 13. Both HSP105-alpha and HSP105-beta are upregulated in HeLa cells exposed to heat shock. HSP105-alpha, but not HSP105-beta, is also upregulate in response to other cell stresses. Following heat shock, HSP105 relocalizes from a cytoplasmic to perinuclear position. Besides, HSP110 may thus constitute a major determinant for both prognosis and treatment response in colorectal cancer.

UniProt: Q92598