HMGB2 Antikörper (AA 64-97)

Produktnummer ABIN7876263

Der Kaninchen Polyklonal anti-HMGB2 Antikörper wird verwendet zum Nachweis von HMGB2 in Proben von Zebrafisch (Danio rerio). Er wurde validiert für WB und IHC (p).

Kurzübersicht für HMGB2 Antikörper (AA 64-97) (ABIN7876263)

Target: HMGB2 (High Mobility Group Box 2 (HMGB2))

Reaktivität: Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HMGB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-HMGB2 Antikörper

Bindungsspezifität: AA 64-97

Verwendungszweck: Zebrafish Hmgb2 Antibody / Hmgb2a / Hmgb2b

Aufreinigung: Antigen affinity chromatography

Immunogen: An E.coli-derived zebrafish Hmgb2a/b recombinant protein (amino acids K64-R97) was used as the immunogen for the Zebrafish Hmgb2 antibody. This antibody will detect the a and b isoforms.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Zebrafish Hmgb2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Zebrafish Hmgb2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu HMGB2

Target: HMGB2 (High Mobility Group Box 2 (HMGB2))

Andere Bezeichnung: Hmgb2

Hintergrund: High-mobility group protein B2, also known as high-mobility group protein 2 (HMG-2), is a protein that in humans is encoded by the HMGB2 gene. This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.

UniProt: Q32PT3

Pathways: Cellular Response to Molecule of Bacterial Origin