DUOX2 Antikörper (AA 63-403)

Produktnummer ABIN7876239

Der Kaninchen Polyklonal anti-DUOX2 Antikörper wird verwendet zum Nachweis von DUOX2 in Proben von Ratte und Maus. Er wurde validiert für WB, ELISA und IHC (p).

Kurzübersicht für DUOX2 Antikörper (AA 63-403) (ABIN7876239)

Target: DUOX2 (Dual Oxidase 2 (DUOX2))

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DUOX2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-DUOX2 Antikörper

Bindungsspezifität: AA 63-403

Verwendungszweck: Duox2 Antibody

Aufreinigung: Affinity purified

Immunogen: An E. coli-derived mouse protein (amino acids A63-D403) was used as the immunogen for the Duox2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Duox2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Duox2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu DUOX2

Target: DUOX2 (Dual Oxidase 2 (DUOX2))

Andere Bezeichnung: Duox2

Hintergrund: Dual oxidase 2, also known as DUOX2 or ThOX2 (for thyroid oxidase), is an enzyme that in humans is encoded by the DUOX2 gene. The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX1. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain.

UniProt: B7ZWM4

Pathways: Thyroid Hormone Synthesis