DLL4
Reaktivität: Human
WB, ELISA
Wirt: Maus
Monoclonal
2E2
unconjugated
Applikationshinweise
The stated application concentrations are suggested starting points. Titration of the DLL4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Aliquot the DLL4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Target
DLL4
(delta-Like 4 (DLL4))
Andere Bezeichnung
DLL4
Hintergrund
Delta-like protein 4 is involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis, negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation is required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. During spinal cord neurogenesis, inhibits V2a interneuron fate. [UniProt]