NCOR2 Antikörper (AA 6-2148)
Kurzübersicht für NCOR2 Antikörper (AA 6-2148) (ABIN7875945)
Target
Alle NCOR2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 6-2148
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Verwendungszweck
- NCOR2 Antibody / Nuclear receptor corepressor 2 / SMRT
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Aufreinigung
- Antigen affinity purified
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Immunogen
- E. coli-derived recombinant human protein (amino acids Q6-H2148) was used as the immunogen for the NCOR2 antibody.
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Isotyp
- IgG
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Applikationshinweise
- Optimal dilution of the NCOR2 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- After reconstitution, the NCOR2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))
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Andere Bezeichnung
- NCOR2
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Hintergrund
- This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.
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UniProt
- Q9Y618
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Pathways
- Notch Signalweg, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
Target
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