TYK2 Antikörper (AA 581-719)

Produktnummer ABIN7875863

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch TYK2 in WB, ELISA und FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für TYK2 Antikörper (AA 581-719) (ABIN7875863)

Target: TYK2 (Tyrosine Kinase 2 (TYK2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TYK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-TYK2 Antikörper

Bindungsspezifität: AA 581-719

Verwendungszweck: TYK2 Antibody / Non-receptor tyrosine-protein kinase TYK2

Aufreinigung: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids F581-A719) was used as the immunogen for the TYK2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the TYK2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the TYK2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu TYK2

Target: TYK2 (Tyrosine Kinase 2 (TYK2))

Andere Bezeichnung: TYK2

Hintergrund: Non-receptor tyrosine-protein kinase TYK2 is an enzyme that in humans is encoded by the TYK2 gene. This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also a component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with Immunodeficiency 35.

UniProt: P29597

Pathways: JAK-STAT Signalweg, Hepatitis C