C1S Antikörper (AA 560-589)

Produktnummer ABIN7875782

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch C1S in WB und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für C1S Antikörper (AA 560-589) (ABIN7875782)

Target: C1S (Complement Component 1, S Subcomponent (C1S))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C1S Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-C1S Antikörper

Bindungsspezifität: AA 560-589

Verwendungszweck: C1S Antibody / Complement C1s subcomponent

Immunogen: A portion of amino acids 560-589 from the human protein was used as the immunogen for the C1S antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the C1S antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide and 50 % glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store the C1S antibody at -20oC.

Details zu C1S

Target: C1S (Complement Component 1, S Subcomponent (C1S))

Andere Bezeichnung: C1S

Hintergrund: C1S, also called Complement C1s subcomponent, is a serine protease enzyme that plays a significant role in the activation of the Complement system, which is a part of the innate immune system. C1S is a key component of the C1 complex, which is the first step in the Complement activation cascade. One of the main functions of C1S is to cleave C4 and C2 proteins, leading to the formation of the C3 convertase enzyme. This enzyme then cleaves C3 protein into two parts, C3a and C3b, which mediate various immune responses such as inflammation, opsonization, and cell lysis. Overall, the activation of the Complement system through C1S plays a critical role in enhancing the immune response and clearing pathogens from our bodies. In addition to its role in immune defense, C1S has also been implicated in other physiological processes such as inflammation, tissue repair, and development. Dysregulation of C1S activity has been linked to various diseases, including autoimmune disorders, inflammatory conditions, and infectious diseases.

UniProt: P09871

Pathways: Komplementsystem