CD166 Antikörper (AA 54-509)

Produktnummer ABIN7875654

Der Kaninchen Polyklonal anti-CD166 Antikörper wird verwendet zum Nachweis von CD166 in Proben von Zebrafisch (Danio rerio). Er wurde validiert für WB und IHC (p).

Kurzübersicht für CD166 Antikörper (AA 54-509) (ABIN7875654)

Target: CD166 (ALCAM) (Activated Leukocyte Cell Adhesion Molecule (ALCAM))

Reaktivität: Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD166 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-CD166 Antikörper

Bindungsspezifität: AA 54-509

Verwendungszweck: Zebrafish Alcama Antibody / Neurolin

Aufreinigung: Antigen affinity chromatography

Immunogen: E. coli-derived zebrafish Alcama recombinant protein (amino acids K54-I509) was used as the immunogen for the Zebrafish Alcama antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Zebrafish Alcama antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Zebrafish Alcama antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu CD166

Target: CD166 (ALCAM) (Activated Leukocyte Cell Adhesion Molecule (ALCAM))

Andere Bezeichnung: Alcama

Hintergrund: Activated leukocyte cell adhesion molecule a (Alcama), also known as Neurolin, is a member of the immunoglobulin superfamily of cell adhesion molecules. In zebrafish (Danio rerio), Alcama plays a vital role in axon guidance, cell-cell adhesion, and tissue morphogenesis, particularly during the development of the nervous system, vasculature, and hematopoietic system.

Alcama is prominently expressed in developing neurons, where it mediates axon fasciculation and growth cone navigation, facilitating the formation of organized neuronal tracts. In addition to its role in neurodevelopment, zebrafish Alcama is expressed in vascular endothelial cells and hematopoietic stem and progenitor cells (HSPCs), where it contributes to vasculogenesis, vascular remodeling, and stem cell niche formation.

Due to its conserved structure and multifunctional roles, zebrafish Alcama is a valuable model for studying cell adhesion dynamics, nervous system wiring, hematopoietic development, and angiogenesis. It is also used in research related to immune cell migration, axon pathfinding disorders, and regenerative medicine.

UniProt: Q90460