DYRK2 Antikörper (AA 521-549)
Kurzübersicht für DYRK2 Antikörper (AA 521-549) (ABIN7875581)
Target
Alle DYRK2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 521-549
-
Verwendungszweck
- DYRK2 Antibody
-
Aufreinigung
- Antigen affinity purified
-
Immunogen
- A portion of amino acids 521-549 from the mouse protein was used as the immunogen for the DYRK2 antibody.
-
Isotyp
- Ig Fraction
-
-
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (AA 105-135), (N-Term) antibody
DYRK2 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB3008 unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (AA 521-549), (C-Term) antibodyDYRK2 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB34467 unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (AA 1-100) antibodyDYRK2 Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 6E2 unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (AA 1-100) antibodyDYRK2 Reaktivität: Human WB, ELISA, IHC (p) Wirt: Maus Monoclonal 2F9 unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (AA 1-100) antibodyDYRK2 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 4G11 unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (AA 1-100) antibodyDYRK2 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 2F9 unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (AA 502-601) antibodyDYRK2 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (C-Term) antibodyDYRK2 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (C-Term) antibodyDYRK2 Reaktivität: Human WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (AA 434-483) antibodyDYRK2 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Schwein WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
-
-
Applikationshinweise
- The stated application concentrations are suggested starting points. Titration of the DYRK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Aliquot the DYRK2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
-
-
- DYRK2 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2))
-
Andere Bezeichnung
- DYRK2
-
Hintergrund
- Role in the regulation of cellular growth and/or development. Regulates TP53 by phosphorylation on Ser-46 to induce apoptosis in response to DNA damage, functioning downstream of ATM. Inactivates GYS1 by phosphorylation at Ser-641, and potentially also a second phosphorylation site, thus regulating glycogen synthesis. Phosphorylates EIF2B5 at Ser-544, enabling its subsequent phosphorylation and inhibition by GSK3, and may play a more general role in the priming of GSK3 substrates (By similarity).
-
UniProt
- Q5U4C9
-
Pathways
- Regulation of Carbohydrate Metabolic Process
Target
-
