Glutaminase Antikörper (AA 516-545)

Produktnummer ABIN7875535

Der Kaninchen Polyklonal anti-Glutaminase Antikörper (ABIN7875535) detektiert spezifisch Glutaminase in WB, IF, FACS und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für Glutaminase Antikörper (AA 516-545) (ABIN7875535)

Target: Glutaminase (GLS)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Glutaminase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Glutaminase Antikörper

Bindungsspezifität: AA 516-545

Verwendungszweck: Glutaminase Antibody / GLS

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 516-545 from the human protein were used as the immunogen for the Glutaminase antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the Glutaminase antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Glutaminase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu Glutaminase

Target: Glutaminase (GLS)

Andere Bezeichnung: Glutaminase

Hintergrund: Sahai (1983) demonstrated phosphate-activated glutaminase (EC 3.5.1.2) in human platelets. It is the major enzyme yielding glutamate from glutamine. Significance of the enzyme derives from its possible implication in behavior disturbances in which glutamate acts as a neurotransmitter (Prusiner, 1981). High heritability of platelet glutaminase was indicated by studies of Sahai and Vogel (1983) [PubMed 6682827] who found an intraclass correlation coefficient of 0.96 for monozygotic twins and 0.53 for dizygotic twins.

UniProt: O94925

Pathways: Feeding Behaviour, Dicarboxylic Acid Transport, Warburg Effekt