PLA2G1B Antikörper (AA 513-541)

Produktnummer ABIN7875533

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PLA2G1B in WB, IF, FACS und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für PLA2G1B Antikörper (AA 513-541) (ABIN7875533)

Target: PLA2G1B (Phospholipase A2, Group IB (PLA2G1B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLA2G1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-PLA2G1B Antikörper

Bindungsspezifität: AA 513-541

Verwendungszweck: Phospholipase A2 Antibody / PLA2G4A / cPLA2

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 513-541 from the human protein was used as the immunogen for the Phospholipase A2 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the Phospholipase A2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Phospholipase A2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu PLA2G1B

Target: PLA2G1B (Phospholipase A2, Group IB (PLA2G1B))

Andere Bezeichnung: Phospholipase A2

Hintergrund: PLA2G4A is a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles.

UniProt: P47712

Pathways: Inositol Metabolic Process, VEGF Signaling