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Glypican 3 Antikörper (AA 511-580) (CF®555)

Der CF®555-konjugierte Maus Monoklonal anti-Glypican 3 Antikörper (Klon SPM595) (ABIN7875532) detektiert spezifisch Glypican 3 in FACS und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human.
Produktnummer ABIN7875532
642,40 €
Zzgl. Versandkosten 20,00 € und MwSt
100 tests
Lieferung nach: Deutschland
Lieferung in 6 bis 9 Werktagen

Kurzübersicht für Glypican 3 Antikörper (AA 511-580) (CF®555) (ABIN7875532)

Target

Alle Glypican 3 (GPC3) Antikörper anzeigen
Glypican 3 (GPC3)

Reaktivität

  • 232
  • 65
  • 55
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 134
  • 79
  • 16
  • 4
  • 3
  • 1
  • 1
Maus

Klonalität

  • 145
  • 84
  • 5
Monoklonal

Konjugat

  • 116
  • 17
  • 10
  • 7
  • 7
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Glypican 3 Antikörper ist konjugiert mit CF®555

Applikation

  • 110
  • 93
  • 88
  • 77
  • 59
  • 30
  • 22
  • 19
  • 13
  • 6
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Immunofluorescence (IF)

Klon

SPM595
  • Bindungsspezifität

    • 23
    • 16
    • 16
    • 12
    • 8
    • 7
    • 7
    • 6
    • 6
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 511-580

    Verwendungszweck

    Glypican 3 Antibody

    Aufreinigung

    Protein G affinity chromatography

    Immunogen

    A recombinant fragment containing amino acids 511-580 from the human protein was used as the immunogen for the Glypican-3 antibody.

    Isotyp

    IgG1, kappa
  • Applikationshinweise

    Optimal dilution of the Glypican 3 antibody should be determined by the researcher.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    500 µL at 0.1 mg/mL with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Store the Glypican 3 antibody at 2-8oC, protected from light.
  • Target

    Glypican 3 (GPC3)

    Andere Bezeichnung

    Glypican 3

    Hintergrund

    Glypican-3 (GPC3) is a glycosylphospatidyl inositol-anchored membrane protein, which may also be found in a secreted form. Anti-GPC3 has been identified as a useful tumor marker for the diagnosis of hepatocellular carcinoma (HCC), hepatoblastoma, melanoma, testicular germ cell tumors, and Wilms tumor and hepatoblastoma, with a low or undetectable expression in normal adjacent tissue. In patients with thyroid cancer, expression of GPC3 is dramatically enhanced in certain types of cancers: 100 % in follicular carcinoma and 70 % in papillary carcinoma. Expression of GPC3 in follicular carcinoma is significantly higher than that of follicular adenoma. In contrast, GPC3 is not expressed in anaplastic carcinoma.

    UniProt

    P51654

    Pathways

    Glycosaminoglycan Metabolic Process
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