PRP19 Antikörper (AA 51-359)
Kurzübersicht für PRP19 Antikörper (AA 51-359) (ABIN7875518)
Target
Alle PRP19 (PRPF19) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 51-359
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Verwendungszweck
- SNEV Antibody / PRP19 / NMP200
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Aufreinigung
- Antigen affinity purified
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Immunogen
- E. coli-derived recombinant human protein (amino acids Q51-H359) was used as the immunogen for the SNEV antibody.
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Isotyp
- IgG
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Applikationshinweise
- Optimal dilution of the SNEV antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- After reconstitution, the SNEV antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PRP19 (PRPF19) (Pre-mRNA Processing Factor 19 (PRPF19))
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Andere Bezeichnung
- SNEV
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Hintergrund
- Pre-mRNA-processing factor 19, also called PRP19, SNEV (Senescence evasion factor) and NMP200 (Nuclear matrix protein 200), is a protein that in humans is encoded by the PRPF19 gene. Enables identical protein binding activity and ubiquitin-ubiquitin ligase activity. Involved in several processes, including DNA damage checkpoint signaling, cellular protein metabolic process, and mRNA splicing, via spliceosome. Acts upstream of or within protein polyubiquitination. Located in cytoplasm, nuclear speck, and site of double-strand break. Part of Prp19 complex and U2-type catalytic step 2 spliceosome. Colocalizes with DNA replication factor A complex.
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UniProt
- Q9UMS4
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Pathways
- Ribonucleoprotein Complex Subunit Organization
Target
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