BIRC6 Antikörper (AA 4810-4844)

Produktnummer ABIN7875225

Der Kaninchen Polyklonal anti-BIRC6 Antikörper wird verwendet zum Nachweis von BIRC6 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für BIRC6 Antikörper (AA 4810-4844) (ABIN7875225)

Target: BIRC6 (Baculoviral IAP Repeat-Containing 6 (BIRC6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BIRC6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BIRC6 Antikörper

Bindungsspezifität: AA 4810-4844

Verwendungszweck: BIRC6 Antibody (C-Terminal Region)

Aufreinigung: Antigen affinity

Immunogen: A portion of amino acids 4810-4844 from human BIRC6 was used as the immunogen for the BIRC6 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the BIRC6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the BIRC6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu BIRC6

Target: BIRC6 (Baculoviral IAP Repeat-Containing 6 (BIRC6))

Andere Bezeichnung: BIRC6

Hintergrund: Baculoviral IAP repeat-containing protein 6 / APOLLON is an anti-apoptotic protein which can regulate cell death by controlling caspases and by acting as an E3 ubiquitin-protein ligase. Has an unusual ubiquitin conjugation system in that it could combine in a single polypeptide, ubiquitin conjugating (E2) with ubiquitin ligase (E3) activity, forming a chimeric E2/E3 ubiquitin ligase. Its tragets include CASP9 and DIABLO/SMAC. Acts as an inhibitor of CASP3, CASP7 and CASP9. Important regulator for the final stages of cytokinesis. Crucial for normal vesicle targeting to the site of abscission, but also for the integrity of the midbody and the midbody ring, and its striking ubiquitin modification. [UniProt]

UniProt: Q9NR09