BIRC6 Antikörper (AA 4810-4844)

Produktnummer ABIN6243063

Der Kaninchen Polyklonal anti-BIRC6 Antikörper wird verwendet zum Nachweis von BIRC6 in Proben von Human. Er wurde validiert für WB und FACS.

Kurzübersicht für BIRC6 Antikörper (AA 4810-4844) (ABIN6243063)

Target: BIRC6 (Baculoviral IAP Repeat-Containing 6 (BIRC6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BIRC6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Klon: RB56699

Produktdetails anti-BIRC6 Antikörper

Bindungsspezifität: AA 4810-4844

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This BIRC6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 4810-4844 amino acids from human BIRC6.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. FC: 1:25

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu BIRC6

Target: BIRC6 (Baculoviral IAP Repeat-Containing 6 (BIRC6))

Andere Bezeichnung: BIRC6

Hintergrund: Anti-apoptotic protein which can regulate cell death by controlling caspases and by acting as an E3 ubiquitin-protein ligase. Has an unusual ubiquitin conjugation system in that it could combine in a single polypeptide, ubiquitin conjugating (E2) with ubiquitin ligase (E3) activity, forming a chimeric E2/E3 ubiquitin ligase. Its tragets include CASP9 and DIABLO/SMAC. Acts as an inhibitor of CASP3, CASP7 and CASP9. Important regulator for the final stages of cytokinesis. Crucial for normal vesicle targeting to the site of abscission, but also for the integrity of the midbody and the midbody ring, and its striking ubiquitin modification.

Molekulargewicht: 530255

UniProt: Q9NR09