Mesothelin Antikörper (AA 44-497)

Produktnummer ABIN7875019

Der Kaninchen Polyklonal anti-Mesothelin Antikörper (ABIN7875019) detektiert spezifisch Mesothelin in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Maus.

Kurzübersicht für Mesothelin Antikörper (AA 44-497) (ABIN7875019)

Target: Mesothelin (MSLN)

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Mesothelin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Mesothelin Antikörper

Bindungsspezifität: AA 44-497

Verwendungszweck: Msln Antibody / Mesothelin

Aufreinigung: Antigen affinity purified

Immunogen: An E.coli-derived mouse recombinant protein (Q44-K497) was used as the immunogen for the Msln antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Msln antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Msln antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu Mesothelin

Target: Mesothelin (MSLN)

Andere Bezeichnung: Msln

Hintergrund: Mesothelin, also known as MSLN or MPF, is a protein that in humans is encoded by the MSLN gene. This gene is mapped to 16p13.3. This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas.

UniProt: Q61468

Pathways: EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process