GCLM Antikörper (AA 4-263)

Produktnummer ABIN7874664

Der Kaninchen Polyklonal anti-GCLM Antikörper wird verwendet zum Nachweis von GCLM in Proben von Human, Maus und Ratte. Er wurde validiert für WB und ELISA.

Kurzübersicht für GCLM Antikörper (AA 4-263) (ABIN7874664)

Target: GCLM (Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GCLM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-GCLM Antikörper

Bindungsspezifität: AA 4-263

Verwendungszweck: GCLM Antibody / Glutamate-cysteine ligase regulatory subunit

Aufreinigung: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids D4-K263) was used as the immunogen for the GCLM antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the GCLM antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the GCLM antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu GCLM

Target: GCLM (Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))

Andere Bezeichnung: GCLM

Hintergrund: Glutamate-cysteine ligase regulatory subunit is an enzyme that in humans is encoded by the GCLM gene. Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Alternative splicing results in multiple transcript variants encoding different isoforms.

UniProt: P48507