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GCLM Antikörper (C-Term)

Name: GCLM Antikörper (C-Term)
SKU: ABIN653046
Price: 445.5 EUR
Availability: InStock

GCLM Reaktivität: Human, Maus WB, IF, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB22980 unconjugated

Western blot analysis of GCLM Antibody (C-term) (ABIN653046 and ABIN2842657) in 293 cell line and mouse kidney tissue lysates (35 μg/lane). (GCLM Antikörper (C-Term))

IHC (p)

Confocal immunofluorescent analysis of GCLM Antibody (C-term) (ABIN653046 and ABIN2842657) with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). (GCLM Antikörper (C-Term))

Western blot analysis of GCLM (arrow) using rabbit polyclonal GCLM Antibody (C-term) (ABIN653046 and ABIN2842657). (GCLM Antikörper (C-Term))

Anti-GCLM Antibody (C-term) at 1:8000 dilution + Hela whole cell lysate Lysates/proteins at 20 μg per lane. (GCLM Antikörper (C-Term))

IHC (p)

GCLM Antibody (C-term) (ABIN653046 and ABIN2842657) flow cytometric analysis of 293 cells (bottom histogram) compared to a negative control cell (top histogram). (GCLM Antikörper (C-Term))

FACS

7 Abbildungen

(1 reference)

Produktnummer ABIN653046

Datenblatt (PDF)

Target Alle GCLM Antikörper anzeigen

GCLM (Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))
Bindungsspezifität
11

7

7

7

6

2

1

1

1

1

1

1

1

1
AA 246-274, C-Term
Reaktivität
64

33

26

3

3

2

2

2

2

2

2

1
Human, Maus
Wirt
58

6
Kaninchen
Passende Sekundärantikörper
Klonalität
50

14
Polyklonal
Konjugat
30

5

4

3

3

3

3

3

3

3

2

2
Dieser GCLM Antikörper ist unkonjugiert
Applikation
39

28

25

18

15

8

7

5

2

2

1

1

1
Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen

This GCLM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 246-274 amino acids from the C-terminal region of human GCLM.

Klon

RB22980

Isotyp

Ig Fraction
anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (AA 40-251) antibody
GCLM Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (AA 1-274), (Regulatory Subunit) antibody
GCLM Reaktivität: Human WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (AA 1-274) antibody
GCLM Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 2B8 unconjugated

anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (AA 245-274), (C-Term) antibody
GCLM Reaktivität: Human WB, IF, FACS, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated

anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (AA 1-274) antibody
GCLM Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated

anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (N-Term) antibody
GCLM Reaktivität: Human, Maus, Ratte, Schwein WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated

anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (AA 1-274) antibody
GCLM Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated

anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (AA 182-231) antibody
GCLM Reaktivität: Human, Maus, Ratte, Rind (Kuh), Affe, Kaninchen, Zebrafisch (Danio rerio), Hund, Meerschweinchen, Pferd, Schwein, Fledermaus WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) antibody
GCLM Reaktivität: Human, Maus IHC Wirt: Kaninchen Polyclonal unconjugated

anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (AA 1-274) antibody
GCLM Reaktivität: Human WB, ELISA, IF, ICC Wirt: Maus Monoclonal AT2D12 unconjugated

Applikationshinweise

IF: 1:10~50. WB: 1:1000. WB: 1:1000. WB: 1:8000. IHC-P: 1:25. IHC-P: 1:25. FC: 1:10~50

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit

6 months
Chen, Jiang, Hu, Zhang: "The protective role of resveratrol in the sodium arsenite-induced oxidative damage via modulation of intracellular GSH homeostasis." in: Biological trace element research, Vol. 155, Issue 1, pp. 119-31, (2014) (PubMed).
Target

GCLM (Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))

Andere Bezeichnung

GCLM (GCLM Produkte)

Synonyme

Glclr antikoerper, GLCLR antikoerper, id:ibd3182 antikoerper, wu:fi24c07 antikoerper, zgc:55903 antikoerper, AI649393 antikoerper, Gcmc antikoerper, glutamate-cysteine ligase regulatory subunit antikoerper, glutamate cysteine ligase, modifier subunit antikoerper, glutamate-cysteine ligase modifier subunit antikoerper, glutamate-cysteine ligase, modifier subunit antikoerper, glutamate-cysteine ligase, modifier subunit L homeolog antikoerper, PTRG_09814 antikoerper, Gclm antikoerper, GCLM antikoerper, gclm antikoerper, gclm.L antikoerper

Hintergrund

GCLM known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia.

Molekulargewicht

30727

Gen-ID

2730

NCBI Accession

NP_002052

UniProt

P48507