ARHGEF12 Antikörper (AA 4-254)

Produktnummer ABIN7874663

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ARHGEF12 in ELISA, WB und FACS. Es zeigt Reaktivität gegenüber Proben von Human und Ratte.

Kurzübersicht für ARHGEF12 Antikörper (AA 4-254) (ABIN7874663)

Target: ARHGEF12 (rho Guanine Nucleotide Exchange Factor (GEF) 12 (ARHGEF12))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGEF12 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Flow Cytometry (FACS)

Produktdetails anti-ARHGEF12 Antikörper

Bindungsspezifität: AA 4-254

Verwendungszweck: LARG Antibody / ARHGEF12

Aufreinigung: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids T4-S254) was used as the immunogen for the LARG antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the LARG antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the LARG antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu ARHGEF12

Target: ARHGEF12 (rho Guanine Nucleotide Exchange Factor (GEF) 12 (ARHGEF12))

Andere Bezeichnung: LARG

Hintergrund: Rho guanine nucleotide exchange factor 12 is a protein that in humans is encoded by the ARHGEF12 gene. Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been found for this gene.

UniProt: Q9NZN5

Pathways: Neurotrophin Signalübertragung, Regulation of G-Protein Coupled Receptor Protein Signaling