PDX1 Antikörper (pan)

Produktnummer ABIN7874661

Der Kaninchen Polyklonal anti-PDX1 Antikörper wird verwendet zum Nachweis von PDX1 in Proben von Human. Er wurde validiert für WB, ELISA und FACS.

Kurzübersicht für PDX1 Antikörper (pan) (ABIN7874661)

Target: PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-PDX1 Antikörper

Bindungsspezifität: AA 4-200, pan

Verwendungszweck: PDX1 Antibody / Pancreas/duodenum homeobox protein 1

Aufreinigung: Affinity purified

Immunogen: Recombinant human protein (amino acids E4-K200) was used as the immunogen for the PDX1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the PDX1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the PDX1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu PDX1

Target: PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))

Andere Bezeichnung: PDX1

Hintergrund: PDX1 (pancreatic and duodenal homeobox 1), also known as insulin promoter factor 1, is a transcription factor in the ParaHox gene cluster. The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (IDDM), as well as maturity onset diabetes of the young type 4 (MODY4).

UniProt: P52945

Pathways: Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location