Histone H2A Antikörper (AA 4-121)

Produktnummer ABIN7874656

Der Kaninchen Polyklonal anti-Histone H2A Antikörper (ABIN7874656) detektiert spezifisch Histone H2A in WB und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Zebrafisch (Danio rerio).

Kurzübersicht für Histone H2A Antikörper (AA 4-121) (ABIN7874656)

Target: Histone H2A

Reaktivität: Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Histone H2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Histone H2A Antikörper

Bindungsspezifität: AA 4-121

Verwendungszweck: Zebrafish H2ax Antibody / Histone H2A.X

Aufreinigung: Antigen affinity chromatography

Immunogen: An E.coli-derived zebrafish Histone H2A.X/H2AFX recombinant protein (amino acids R4-T121) was used as the immunogen for the Zebrafish H2ax antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Zebrafish H2ax antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Zebrafish H2ax antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu Histone H2A

Target: Histone H2A

Hintergrund: H2A histone family member X (usually abbreviated as H2AX) is a type of histone protein from the H2A family encoded by the H2AFX gene. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.

UniProt: Q7ZUY3