DENND1B Antikörper (AA 39-68)

Produktnummer ABIN7874606

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch DENND1B in WB, FACS und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für DENND1B Antikörper (AA 39-68) (ABIN7874606)

Target: DENND1B (DENN/MADD Domain Containing 1B (DENND1B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DENND1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-DENND1B Antikörper

Bindungsspezifität: AA 39-68

Verwendungszweck: DENND1B Antibody

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 39-68 from the human protein was used as the immunogen for the DENND1B antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the DENND1B antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the DENND1B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu DENND1B

Target: DENND1B (DENN/MADD Domain Containing 1B (DENND1B))

Andere Bezeichnung: DENND1B

Hintergrund: Clathrin-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 and bind to clathrin and clathrin adaptor protein-2. Thus, connecdenns link RAB35 activation with the clathrin machinery.

UniProt: Q6P3S1