DENND1B Antikörper (N-Term)
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- Target Alle DENND1B Antikörper anzeigen
- DENND1B (DENN/MADD Domain Containing 1B (DENND1B))
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Bindungsspezifität
- AA 39-68, N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser DENND1B Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Homologie
- M
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This DENND1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-68 amino acids from the N-terminal region of human DENND1B.
- Klon
- RB28056
- Isotyp
- Ig Fraction
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anti-DENN/MADD Domain Containing 1B (DENND1B) (Center) antibody
DENND1B Reaktivität: Human, Maus WB, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-DENN/MADD Domain Containing 1B (DENND1B) (AA 108-157) antibodyDENND1B Reaktivität: Human, Kaninchen, Rind (Kuh), Hund WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-DENN/MADD Domain Containing 1B (DENND1B) (AA 144-193) antibodyDENND1B Reaktivität: Human, Maus, Kaninchen, Meerschweinchen, Pferd, Hund, Zebrafisch (Danio rerio), Fledermaus, Huhn, Affe, Schwein WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-DENN/MADD Domain Containing 1B (DENND1B) (AA 46-76), (N-Term) antibodyDENND1B Reaktivität: Human WB, FACS, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
anti-DENN/MADD Domain Containing 1B (DENND1B) antibodyDENND1B Reaktivität: Human, Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-DENN/MADD Domain Containing 1B (DENND1B) (AA 1-396) antibodyDENND1B Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
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- Applikationshinweise
- WB: 1:500. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Haltbarkeit
- 6 months
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- Target
- DENND1B (DENN/MADD Domain Containing 1B (DENND1B))
- Andere Bezeichnung
- DENND1B (DENND1B Produkte)
- Synonyme
- C1ORF18 antikoerper, C1orf218 antikoerper, FAM31B antikoerper, 4632404N19Rik antikoerper, 4930467M19Rik antikoerper, 6820401H01Rik antikoerper, F730008N07Rik antikoerper, Fam31b antikoerper, si:ch211-195i21.1 antikoerper, DENN domain containing 1B antikoerper, DENN/MADD domain containing 1B antikoerper, DENND1B antikoerper, dennd1b antikoerper, Dennd1b antikoerper
- Hintergrund
- Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2, see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).
- Molekulargewicht
- 86552
- Gen-ID
- 163486
- NCBI Accession
- NP_001182144, NP_001182145, NP_659414
- UniProt
- Q6P3S1
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