SOCS5 Antikörper (AA 386-536)

Produktnummer ABIN7874548

Der Kaninchen Polyklonal anti-SOCS5 Antikörper (ABIN7874548) detektiert spezifisch SOCS5 in WB, ELISA und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für SOCS5 Antikörper (AA 386-536) (ABIN7874548)

Target: SOCS5 (Suppressor of Cytokine Signaling 5 (SOCS5))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOCS5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-SOCS5 Antikörper

Bindungsspezifität: AA 386-536

Verwendungszweck: SOCS5 Antibody / Suppressor of cytokine signaling 5

Aufreinigung: Antigen affinity purified

Immunogen: Amino acids M386-K536 from the human protein were used as the immunogen for the SOCS5 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the SOCS5 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the SOCS5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu SOCS5

Target: SOCS5 (Suppressor of Cytokine Signaling 5 (SOCS5))

Andere Bezeichnung: SOCS5

Hintergrund: SOCS5 (Suppressor of cytokine signaling 5) is a member of the SOCS family, a group of intracellular proteins that function as negative regulators of cytokine receptor signaling. SOCS5 contains an SH2 domain and a SOCS box motif, allowing it to interact with activated receptors and associated kinases to modulate JAK-STAT pathway activity. By preventing excessive cytokine signaling, SOCS5 maintains immune system balance and contributes to cellular homeostasis. A SOCS5 antibody is a valuable tool for investigating these regulatory mechanisms.

SOCS5 has been implicated in the regulation of interleukin and growth factor signaling. Its activity helps control cell proliferation, differentiation, and survival. Aberrant expression or dysfunction of SOCS5 has been associated with various pathological conditions, including chronic inflammation, autoimmune disorders, and certain cancers. Using a SOCS5 antibody enables researchers to evaluate its expression patterns, molecular interactions, and role in disease development.

In addition to its role in immune regulation, SOCS5 has been shown to influence neural development and epithelial cell signaling, highlighting its multifunctional nature. Studies have indicated that SOCS5 can act as a tumor suppressor in specific contexts, while in other cases, it may contribute to oncogenesis depending on the signaling environment. Employing a SOCS5 antibody allows for precise characterization of these complex roles across different biological systems.

NSJ Bioreagents offers a high-quality SOCS5 antibody validated for applications such as western blot, immunohistochemistry, and immunofluorescence. Selecting a SOCS5 antibody from NSJ Bioreagents ensures reliable performance for studies of cytokine signaling, immune regulation, and cancer biology.

UniProt: O75159

Pathways: JAK-STAT Signalweg, EGFR Signaling Pathway, Positive Regulation of Immune Effector Process