MCM2 Antikörper (AA 381-835)

Produktnummer ABIN7874525

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MCM2 in WB. Es zeigt Reaktivität gegenüber Proben von Zebrafisch (Danio rerio).

Kurzübersicht für MCM2 Antikörper (AA 381-835) (ABIN7874525)

Target: MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))

Reaktivität: Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MCM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MCM2 Antikörper

Bindungsspezifität: AA 381-835

Verwendungszweck: Zebrafish Mcm2 Antibody

Aufreinigung: Antigen affinity chromatography

Immunogen: An E.coli-derived zebrafish Mcm2 recombinant protein (amino acids A381-R835) was used as the immunogen for the Zebrafish Mcm2 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Zebrafish Mcm2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Zebrafish Mcm2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu MCM2

Target: MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))

Andere Bezeichnung: Mcm2

Hintergrund: MCM2 (MINICHROMOSOME MAINTENANCE, S. CEREVISIAE, HOMOLOG OF, 2), also known as MITOTIN, CDCL1 or BM28, is a human nuclear protein that plays an important role in 2 crucial steps of the cell cycle, namely, onset of DNA replication and cell division. And it is similar to members of the family of early S-phase proteins. The MCM2 gene is mapped to 3q21.3. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. In the G0 stage, the MCM2 and MCM5 proteins were much less abundant than the MCM7 and MCM3 proteins, which suggests that the MCM proteins are not present in stoichiometric amounts and that only a proportion of these molecules actively participate in cell cycle regulation as part of MCM complexes.

Pathways: DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA