Melanoma gp100 Antikörper (AA 376-502)

Produktnummer ABIN7874472

Der Maus Monoklonal anti-Melanoma gp100 Antikörper wird verwendet zum Nachweis von Melanoma gp100 in Proben von Human. Er wurde validiert für IHC (p).

Kurzübersicht für Melanoma gp100 Antikörper (AA 376-502) (ABIN7874472)

Target: Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Melanoma gp100 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: MSSG95-2

Produktdetails anti-Melanoma gp100 Antikörper

Bindungsspezifität: AA 376-502

Verwendungszweck: Melanoma gp100 Antibody / PMEL17

Aufreinigung: Protein G affinity chromatography

Immunogen: A portion of amino acids 376-502 from the human protein was used as the immunogen for the Melanoma gp100 antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the Melanoma gp100 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the Melanoma gp100 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu Melanoma gp100

Target: Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))

Andere Bezeichnung: Melanoma gp100

Hintergrund: PMEL17/Melanoma gp100/SILV plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity. [UniProt]

UniProt: P40967