INHBB Antikörper (AA 369-397)

Produktnummer ABIN7874377

Der Kaninchen Polyklonal anti-INHBB Antikörper (ABIN7874377) detektiert spezifisch INHBB in WB und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für INHBB Antikörper (AA 369-397) (ABIN7874377)

Target: INHBB (Inhibin, beta B (INHBB))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser INHBB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-INHBB Antikörper

Bindungsspezifität: AA 369-397

Verwendungszweck: Inhibin beta B chain Antibody / INHBB

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 369-397 from the human protein was used as the immunogen for the Inhibin beta B chain antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the Inhibin beta B chain antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Inhibin beta B chain antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu INHBB

Target: INHBB (Inhibin, beta B (INHBB))

Andere Bezeichnung: Inhibin beta B chain

Hintergrund: The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion.

UniProt: P09529

Pathways: Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion