NUP214 Antikörper (AA 36-374)

Produktnummer ABIN7874312

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch NUP214 in WB, IF, ELISA und FACS. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für NUP214 Antikörper (AA 36-374) (ABIN7874312)

Target: NUP214 (Nucleoporin 214kDa (NUP214))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NUP214 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), ELISA, Flow Cytometry (FACS)

Produktdetails anti-NUP214 Antikörper

Bindungsspezifität: AA 36-374

Verwendungszweck: NUP214 Antibody / Nucleoporin 214

Aufreinigung: Affinity purified

Immunogen: Recombinant human protein (amino acids K36-E374) was used as the immunogen for the NUP214 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the NUP214 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the NUP214 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu NUP214

Target: NUP214 (Nucleoporin 214kDa (NUP214))

Andere Bezeichnung: NUP214

Hintergrund: Nucleoporin 214 (Nup2014) is a protein that in humans is encoded by the NUP214 gene. The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. This gene is a member of the FG-repeat-containing nucleoporins. The protein encoded by this gene is localized to the cytoplasmic face of the nuclear pore complex where it is required for proper cell cycle progression and nucleocytoplasmic transport. The 3' portion of this gene forms a fusion gene with the DEK gene on chromosome 6 in a t(6,9) translocation associated with acute myeloid leukemia and myelodysplastic syndrome. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.

UniProt: P35658

Pathways: Protein targeting to Nucleus, SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion