NUP214 Antikörper (AA 750-1030)
Kurzübersicht für NUP214 Antikörper (AA 750-1030) (ABIN6144958)
Target
Alle NUP214 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 750-1030
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Sequenz
- FLLEIKETTE SLHGDISSLK TTLLEGFAGV EEAREQNERN RDSGYLHLLY KRPLDPKSEA QLQEIRRLHQ YVKFAVQDVN DVLDLEWDQH LEQKKKQRHL LVPERETLFN TLANNREIIN QQRKRLNHLV DSLQQLRLYK QTSLWSLSSA VPSQSSIHSF DSDLESLCNA LLKTTIESHT KSLPKVPAKL SPMKQAQLRN FLAKRKTPPV RSTAPASLSR SAFLSQRYYE DLDEVSSTSS VSQSLESEDA RTSCKDDEAV VQAPRHAPVV RTPSIQPSLL P
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 750-1030 of human NUP214 (NP_005076.3).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IF,1:50 - 1:100
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- NUP214 (Nucleoporin 214kDa (NUP214))
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Andere Bezeichnung
- NUP214
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Hintergrund
- The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. This gene is a member of the FG-repeat-containing nucleoporins. The protein encoded by this gene is localized to the cytoplasmic face of the nuclear pore complex where it is required for proper cell cycle progression and nucleocytoplasmic transport. The 3' portion of this gene forms a fusion gene with the DEK gene on chromosome 6 in a t(6,9) translocation associated with acute myeloid leukemia and myelodysplastic syndrome. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.,NUP214,CAIN,CAN,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,NUP214
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Molekulargewicht
- 212 kDa/213 kDa/215 kDa
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Gen-ID
- 8021
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UniProt
- P35658
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Pathways
- Protein targeting to Nucleus, SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion
Target
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