SPTA1 Antikörper (AA 356-475)

Produktnummer ABIN7874267

Dieser Maus Monoklonal Antikörper detektiert spezifisch SPTA1 in WB, ELISA und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für SPTA1 Antikörper (AA 356-475) (ABIN7874267)

Target: SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SPTA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: SPTA1-1832

Produktdetails anti-SPTA1 Antikörper

Bindungsspezifität: AA 356-475

Verwendungszweck: Spectrin alpha 1 Antibody / SPTA1 (azide and preservative free)

Aufreinigung: Protein G affinity chromatography

Immunogen: A portion of amino acids 356-475 from the human protein was used as the immunogen for the Spectrin alpha 1 antibody.

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Spectrin alpha 1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the Spectrin alpha 1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu SPTA1

Target: SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))

Andere Bezeichnung: Spectrin alpha 1

Hintergrund: Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. Spectrins function as membrane organizers and stabilizers, composed of non-homologous and chains, which aggregate side-to-side in an anti-parallel fashion to form dimers, tetramers and higher polymers. Spectrin Ia and spectrin Ib are present in erythrocytes, whereas spectrin IIa (also designated fodrin alpha) and spectrin IIb (also designated fodrin beta) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function.

UniProt: P02549

Pathways: Regulation of Actin Filament Polymerization