TK2 Antikörper (AA 34-265)

Produktnummer ABIN7874071

Der Kaninchen Polyklonal anti-TK2 Antikörper (ABIN7874071) detektiert spezifisch TK2 in WB, ELISA und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für TK2 Antikörper (AA 34-265) (ABIN7874071)

Target: TK2 (Thymidine Kinase 2, Mitochondrial (TK2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-TK2 Antikörper

Bindungsspezifität: AA 34-265

Verwendungszweck: Thymidine Kinase 2 Antibody / TK2

Aufreinigung: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids V34-P265) was used as the immunogen for the Thymidine Kinase 2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Thymidine Kinase 2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Thymidine Kinase 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu TK2

Target: TK2 (Thymidine Kinase 2, Mitochondrial (TK2))

Andere Bezeichnung: Thymidine Kinase 2

Hintergrund: Thymidine kinase 2, mitochondrial is a protein that in humans is encoded by the TK2 gene. This gene encodes a deoxyribonucleoside kinase that specifically phosphorylates thymidine, deoxycytidine, and deoxyuridine. The encoded enzyme localizes to the mitochondria and is required for mitochondrial DNA synthesis. Mutations in this gene are associated with a myopathic form of mitochondrial DNA depletion syndrome. Alternate splicing results in multiple transcript variants encoding distinct isoforms, some of which lack transit peptide, so are not localized to mitochondria.

UniProt: O00142

Pathways: Mitotic G1-G1/S Phases