FOXO3 Antikörper (AA 312-537)
Kurzübersicht für FOXO3 Antikörper (AA 312-537) (ABIN7873851)
Target
Alle FOXO3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 312-537
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Verwendungszweck
- FKHRL1 Antibody / FOXO3A
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Aufreinigung
- Antigen affinity purified
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Immunogen
- E. coli-derived recombinant human protein (amino acids R312-Q537) was used as the immunogen for the FKHRL1 antibody.
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Isotyp
- IgG
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anti-Forkhead Box O3 (FOXO3) (pSer253) antibody
FOXO3 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (C-Term) antibodyVerified FOXO3 Reaktivität: Human WB, IHC, ELISA Wirt: Ziege Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (pSer318), (pSer321) antibodyFOXO3 Reaktivität: Human, Ratte WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (C-Term) antibodyKO Validated FOXO3 Reaktivität: Human WB, IF, IHC (p), ICC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (N-Term) antibodyFOXO3 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Schwein, Schaf, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (AA 471-673) antibodyFOXO3 Reaktivität: Human, Ratte WB, IHC, IF, ICC, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (N-Term) antibodyFOXO3 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (AA 361-460) antibodyFOXO3 Reaktivität: Human ELISA, IF, IHC (p) Wirt: Maus Monoclonal 1E11 unconjugated
anti-Forkhead Box O3 (FOXO3) (AA 361-460) antibodyFOXO3 Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 1F6 unconjugated
anti-Forkhead Box O3 (FOXO3) antibodyFOXO3 Reaktivität: Human WB, IHC, ELISA, IF Wirt: Kaninchen Monoclonal 1E2 unconjugated Recombinant Antibody
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Applikationshinweise
- Optimal dilution of the FKHRL1 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- After reconstitution, the FKHRL1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- FOXO3 (Forkhead Box O3 (FOXO3))
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Andere Bezeichnung
- FKHRL1
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Hintergrund
- Forkhead box O3, also known as FKHRL1 (Forkhead in rhabdomyosarcoma-like 1) or FOXO3a, is a human protein encoded by the FOXO3 gene. FOXO3 belongs to the O subclass of the forkhead family of transcription factors which are characterized by a distinct fork head DNA-binding domain. It is mapped to 6q21. This protein likely functions as a trigger for apoptosis through upregulation of genes necessary for cell death, such as Bim and PUMA, or downregulation of anti-apoptotic proteins such as FLIP. In mammals FOXO3 regulates the resistance of cells to stress by inducing DNA repair and thereby may also affect organismal life span. In addition, it is thought that FOXO3 is also involved in protection from oxidative stress by upregulating antioxidants such as catalase and MnSOD.
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UniProt
- O43524
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Pathways
- Zellzyklus, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Carbohydrate Homeostasis
Target
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