PODXL Antikörper (AA 310-447)
Kurzübersicht für PODXL Antikörper (AA 310-447) (ABIN7873810)
Target
Alle PODXL Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Bindungsspezifität
- AA 310-447
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Verwendungszweck
- Podocalyxin Antibody (azide and preservative free)
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Aufreinigung
- Protein G affinity
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Immunogen
- A portion of amino acids 310-447 from the human protein was used as the immunogen for the Podocalyxin antibody.
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Isotyp
- IgG1, kappa
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Applikationshinweise
- Optimal dilution of the Podocalyxin antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store the Podocalyxin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- PODXL (Podocalyxin-Like (PODXL))
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Andere Bezeichnung
- Podocalyxin
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Hintergrund
- Podocalyxin/PODXL is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.
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UniProt
- O00592
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Pathways
- Tube Formation
Target
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