PODXL Antikörper (AA 310-447)
Kurzübersicht für PODXL Antikörper (AA 310-447) (ABIN7873809)
Target
Alle PODXL Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Bindungsspezifität
- AA 310-447
-
Verwendungszweck
- Podocalyxin Antibody / PODXL
-
Aufreinigung
- Protein G affinity chromatography
-
Immunogen
- A recombinant human partial protein (amino acids 310-447) was used as the immunogen for this Podocalyxin antibody.
-
Isotyp
- IgG1, kappa
-
-
-
-
Applikationshinweise
- Optimal dilution of the Podocalyxin antibody should be determined by the researcher.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 0.2 mg/mL
-
Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- Store the Podocalyxin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
-
-
- PODXL (Podocalyxin-Like (PODXL))
-
Andere Bezeichnung
- Podocalyxin
-
Hintergrund
- Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.
-
UniProt
- O00592
-
Pathways
- Tube Formation
Target
-