N-Cadherin Antikörper (AA 308-597)
Kurzübersicht für N-Cadherin Antikörper (AA 308-597) (ABIN7873737)
Target
Alle N-Cadherin (CDH2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Bindungsspezifität
- AA 308-597
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Verwendungszweck
- CD325 Antibody / CDH2 / N-Cadherin (azide and preservative free)
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Aufreinigung
- Protein A/G affinity
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Immunogen
- A portion of amino acids 308-597 was used as the immunogen for the CD325 antibody.
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Isotyp
- IgG2a
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anti-Cadherin 2 (CDH2) (AA 701-800) antibody
CDH2 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio) WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Cadherin 2 (CDH2) antibodyCDH2 Reaktivität: Human, Maus, Hund, Affe WB, IHC, FACS, IHC (p) Wirt: Maus Monoclonal 2G7 unconjugated
anti-Cadherin 2 (CDH2) (AA 750-850) antibodyCDH2 Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Cadherin 2 (CDH2) antibodyCDH2 Reaktivität: Human, Maus, Ratte WB, IHC, FACS, ELISA, ICC Wirt: Maus Monoclonal 5D5 unconjugated
anti-Cadherin 2 (CDH2) (AA 45-238) antibodyCDH2 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Cadherin 2 (CDH2) (AA 160-724) antibodyCDH2 Reaktivität: Human, Maus WB, IP, FACS, ICC Wirt: Kaninchen Monoclonal BLR097G unconjugated Recombinant Antibody
anti-Cadherin 2 (CDH2) (AA 690-770) antibodyCDH2 Reaktivität: Human, Maus, Ratte WB, IHC, IF, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Cadherin 2 (CDH2) (AA 295-414) antibodyCDH2 Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Cadherin 2 (CDH2) (AA 685-784) antibodyCDH2 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Cadherin 2 (CDH2) (Extracellular Domain) antibodyCDH2 Reaktivität: Human, Maus WB, IHC, IF, FACS Wirt: Maus Monoclonal 8C11 unconjugated
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Applikationshinweise
- Optimal dilution of the CD325 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the CD325 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- N-Cadherin (CDH2) (Cadherin 2 (CDH2))
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Andere Bezeichnung
- CD325
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Hintergrund
- Recognizes a protein of ~140 kDa, identified as N-Cadherin (NCAD), also known as CD325. NCAD is a member of the Cadherin superfamily, and consists of five extracellular repeats, a transmembrane domain and a cytoplasmic domain. CD325 deficient mice die at day 10 of gestation and embryos display major heart defects and malformed neural tubes and somites. Consistent with this, CD325 has been implicated in several aspects of cardiac development including the precardiac mesoderm, establishment of left-right symmetry and cardiac looping morphogenesis. Furthermore, CD325 is normally involved in inducing cell cycle arrest and its expression is frequently deregulated in cancer cells.Studies have linked N-cadherin to cancer metastasis by showing the aggressive tumor cells had preferentially turned on N-cadherin as opposed to E- or P-cadherin.
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UniProt
- P19022
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Pathways
- Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Synaptic Membrane
Target
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