OPA1 Antikörper (AA 302-568)

Produktnummer ABIN7873722

Der Kaninchen Polyklonal anti-OPA1 Antikörper wird verwendet zum Nachweis von OPA1 in Proben von Zebrafisch (Danio rerio). Er wurde validiert für WB und IHC (p).

Kurzübersicht für OPA1 Antikörper (AA 302-568) (ABIN7873722)

Target: OPA1 (Optic Atrophy 1 (Autosomal Dominant) (OPA1))

Reaktivität: Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OPA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-OPA1 Antikörper

Bindungsspezifität: AA 302-568

Verwendungszweck: Zebrafish Opa1 Antibody / Dynamin-like GTPase Opa1

Aufreinigung: Antigen affinity chromatography

Immunogen: An E.coli-derived zebrafish Opa1 recombinant protein (amino acids D302-Q568) was used as the immunogen for the Zebrafish Opa1 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Zebrafish Opa1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Zebrafish Opa1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu OPA1

Target: OPA1 (Optic Atrophy 1 (Autosomal Dominant) (OPA1))

Andere Bezeichnung: Opa1

Hintergrund: Dynamin-like 120 kDa protein, mitochondrial is a protein that in humans is encoded by the OPA1 gene. It is mapped to 3q29. This protein regulates mitochondrial fusion and cristae structure in the inner mitochondrial membrane (IMM) and contributes to ATP synthesis and apoptosis. This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene.

UniProt: Q5U3A7

Pathways: Tube Formation