HRS (HRS) (AA 3-777) Antikörper

Produktnummer ABIN7873553

Dieser Maus Monoklonal Antikörper detektiert spezifisch HRS in WB, FACS und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für HRS (HRS) (AA 3-777) Antikörper (ABIN7873553)

Target: HRS

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 6C2E1

Produktdetails

Bindungsspezifität: AA 3-777

Verwendungszweck: HRS Antibody / HGS / HGF-regulated tyrosine kinase substrate

Aufreinigung: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids R3-D777) was used as the immunogen for the HRS antibody.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the HRS antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the HRS antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Antigendetails

Target: HRS

Andere Bezeichnung: HRS

Hintergrund: Hepatocyte growth factor-regulated tyrosine kinase substrate is an enzyme that in humans is encoded by the HGS gene. It is mapped to 17q25.3. The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation.

UniProt: O14964

Pathways: CXCR4-mediated Signaling Events, EGFR Downregulation