HRS (HRS) (AA 301-350), (pTyr334) Antikörper
Kurzübersicht für HRS (HRS) (AA 301-350), (pTyr334) Antikörper (ABIN1531658)
Target
Alle HRS Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 301-350, pTyr334
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Verwendungszweck
- Hrs (phospho Tyr334) Antibody
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Spezifität
- Phospho-Hrs (Y334) Polyclonal Antibody detects endogenous levels of Hrs protein only when phosphorylated at Y334.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human HRS around the phosphorylation site of Tyr334. AA range:301-350
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- HRS
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Andere Bezeichnung
- HRS
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Hintergrund
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Synonyms: HGS, HRS, Hepatocyte growth factor-regulated tyrosine kinase substrate, Hrs, Protein pp110
Background: The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation. [provided by RefSeq, Dec 2010],
Gene Name: HGS
Protein Name: Hepatocyte growth factor-regulated tyrosine kinase substrate
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Molekulargewicht
- 86 kDa
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Gen-ID
- 9146
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OMIM
- 604375
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UniProt
- O14964
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Pathways
- CXCR4-mediated Signaling Events, EGFR Downregulation
Target
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