HRS (HRS) (AA 3-777) Antikörper

Produktnummer ABIN7873552

Der Maus Monoklonal anti-HRS Antikörper (Klon 4B7E2) (ABIN7873552) detektiert spezifisch HRS in WB, IF, FACS und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für HRS (HRS) (AA 3-777) Antikörper (ABIN7873552)

Target: HRS

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 4B7E2

Produktdetails

Bindungsspezifität: AA 3-777

Verwendungszweck: HGF-regulated tyrosine kinase substrate Antibody / HRS / HGS

Aufreinigung: Antigen affinity purified

Immunogen: Recombinant human HGS protein (amino acids R3-D777) was used as the immunogen for the HGF-regulated tyrosine kinase substrate antibody.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the HGF-regulated tyrosine kinase substrate antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the HGF-regulated tyrosine kinase substrate antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Antigendetails

Target: HRS

Andere Bezeichnung: HGF-regulated tyrosine kinase substrate

Hintergrund: Hepatocyte growth factor-regulated tyrosine kinase substrate is an enzyme that in humans is encoded by the HGS gene. It is mapped to 17q25.3. The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation.

UniProt: O14964

Pathways: CXCR4-mediated Signaling Events, EGFR Downregulation