SERBP1 Antikörper (AA 3-139)
Kurzübersicht für SERBP1 Antikörper (AA 3-139) (ABIN7873492)
Target
Alle SERBP1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Bindungsspezifität
- AA 3-139
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Verwendungszweck
- SERBP1 Antibody / PAI-RBP1 (azide and preservative free)
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Aufreinigung
- Protein G affinity chromatography
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Immunogen
- A portion of amino acids 3-139 from the human protein was used as the immunogen for the SERBP1 antibody.
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Isotyp
- IgG2b, kappa
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Applikationshinweise
- Optimal dilution of the SERBP1 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store the SERBP1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- SERBP1 (SERPINE1 mRNA Binding Protein 1 (SERBP1))
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Andere Bezeichnung
- SERBP1
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Hintergrund
- SERBP1 is a membrane-associated protein that localizes to the nucleus, the perinuclear region of the cytoplasm and the plasma membrane. It is believed to play a role in the regulation of mRNA stability, as it specifically binds to the CRS (cyclic nucleotide-responsive sequence) motif of the PAI-1 mRNA and acts to stabilize the mRNA and regulate its expression. In addition, SERBP1 interacts with Mi2-s antiapoptotic action in ovarian cell types. SERBP1 is overexpressed in ovarian cancer, suggesting a possible role in tumorigenesis and tumor metastasis.
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UniProt
- Q8NC51
Target
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