LIG3 Antikörper (AA 297-963)

Produktnummer ABIN7873483

Der Kaninchen Polyklonal anti-LIG3 Antikörper (ABIN7873483) detektiert spezifisch LIG3 in WB, ELISA und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für LIG3 Antikörper (AA 297-963) (ABIN7873483)

Target: LIG3 (Ligase III, DNA, ATP-Dependent (LIG3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LIG3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-LIG3 Antikörper

Bindungsspezifität: AA 297-963

Verwendungszweck: DNA Ligase 3 Antibody / LIG3

Aufreinigung: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids D297-D963) was used as the immunogen for the DNA Ligase 3 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the DNA Ligase 3 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the DNA Ligase 3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu LIG3

Target: LIG3 (Ligase III, DNA, ATP-Dependent (LIG3))

Andere Bezeichnung: DNA Ligase 3

Hintergrund: DNA ligase 3 is an enzyme that, in humans, is encoded by the LIG3 gene. This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized.

UniProt: P49916

Pathways: DNA Reparatur