HIF3A Antikörper (AA 29-480)
Kurzübersicht für HIF3A Antikörper (AA 29-480) (ABIN7873426)
Target
Alle HIF3A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 29-480
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Verwendungszweck
- HIF3A Antibody / Hypoxia-inducible factor 3 alpha
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Aufreinigung
- Affinity purified
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Immunogen
- Recombinant human protein (amino acids Q29-Q480) was used as the immunogen for the HIF3A antibody.
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Isotyp
- IgG
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Applikationshinweise
- Optimal dilution of the HIF3A antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- After reconstitution, the HIF3A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))
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Andere Bezeichnung
- HIF3A
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Hintergrund
- Hypoxia-inducible factor 3 alpha, also called MOP7, is a protein that in humans is encoded by the HIF3A gene. HIF3A is mapped to 19q13.32. This gene involved in adaptive response to hypoxia. HIF3A suppresses hypoxia-inducible expression of HIF1A and EPAS1. It binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters. The complex HIF3A-ARNT activates the transcription of reporter genes driven by HRE. This gene functions as an inhibitor of angiogenesis in the cornea.
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UniProt
- Q9Y2N7
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Pathways
- Warburg Effekt
Target
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