Gephyrin Antikörper (AA 288-735)

Produktnummer ABIN7873329

Der Kaninchen Polyklonal anti-Gephyrin Antikörper wird verwendet zum Nachweis von Gephyrin in Proben von Zebrafisch (Danio rerio). Er wurde validiert für WB und IHC (p).

Kurzübersicht für Gephyrin Antikörper (AA 288-735) (ABIN7873329)

Target: Gephyrin (GPHN)

Reaktivität: Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Gephyrin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Gephyrin Antikörper

Bindungsspezifität: AA 288-735

Verwendungszweck: Zebrafish Gephyrin Antibody / Gphna / Gphnb

Aufreinigung: Antigen affinity chromatography

Immunogen: An E.coli-derived zebrafish GPHNa/b recombinant protein (amino acids V288-L735) was used as the immunogen for the Zebrafish Gephyrin antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Zebrafish Gephyrin antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Zebrafish Gephyrin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu Gephyrin

Target: Gephyrin (GPHN)

Andere Bezeichnung: Gephyrin

Hintergrund: Gephyrin is a protein that in humans is encoded by the GPHN gene. This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described, however, the full-length nature of all transcript variants is not currently known.

UniProt: D3KYK7

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development