RORC Antikörper (AA 286-511)

Produktnummer ABIN7873318

Der Kaninchen Polyklonal anti-RORC Antikörper (ABIN7873318) detektiert spezifisch RORC in WB, ELISA und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für RORC Antikörper (AA 286-511) (ABIN7873318)

Target: RORC (RAR-Related Orphan Receptor C (RORC))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RORC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-RORC Antikörper

Bindungsspezifität: AA 286-511

Verwendungszweck: ROR gamma Antibody / RORC

Aufreinigung: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids Q286-E511) was used as the immunogen for the ROR gamma antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the ROR gamma antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the ROR gamma antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu RORC

Target: RORC (RAR-Related Orphan Receptor C (RORC))

Andere Bezeichnung: ROR gamma

Hintergrund: RAR-related orphan receptor gamma (RORg) is a protein that in humans is encoded by the RORC (RAR-related orphan receptor C) gene. The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene.

UniProt: P51449

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway